FIGURE

Fig. 7

ID

ZDB-FIG-140307-12

Publication

Griffin et al., 1998 - Molecular identification of spadetail: regulation of zebrafish trunk and tail mesoderm formation by T-box genes

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Fig. 7

Synergistic regulation of spt and tbx6 by spt and ntl. Expression of tbx6 (A-D; bud, 10 h.p.f.) and spt (E-H; 95% epiboly, 9.5 h.p.f.). In ntl- embryos expression of tbx6 (B) and spt (F) are similar to WT (A,E) except for broadening of the non-expressing notochord domain (Melby et al., 1997). In addition, spt is no longer prominently expressed by adaxial cells. In spt- embryos, expression of both tbx6 (C) and spt (G) are very weak or absent from hypoblast cells but remain detectable in the tail bud epiblast (*). In spt-;ntl- embryos, expression of tbx6 (D) is entirely undetectable, and spt (H) is only barely detected (arrow).

Expression Data

Genes:	tbx16 tbx16l
Fish:	WT tbx16^b104/b104 (AB) tbxta^b195/b195 tbxta^b195/b195; tbx16^b104/b104
Anatomical Terms:	adaxial cell hypoblast margin mesoderm tail bud epiblast
Stage Range:	90%-epiboly to Bud

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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