FIGURE

Fig. 4

ID

ZDB-FIG-131024-19

Publication

Akitake et al., 2011 - Transgenerational analysis of transcriptional silencing in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Correlation between variegated expression and CpG methylation. (A) In the c368 line, variegation in GFP labeling was observed in F1 larvae (not shown) and was more frequently observed in F2 and F3 larvae compared to other 4Xnr UAS lines (compare with Fig. 3B). Few c368 GFP^high larvae were found in either generation. (B) Fluorescence images and representative DNA bisulfite sequencing data for individual GFP^med and GFP^low c368 F2 larvae at 2 dpf. The upper larvae possess both the c368a and c368b transgenic insertions (Table 2), whereas the bottom two larvae have only the c368a transgene. GFP-labeled individuals carrying only the c368b insertion were not detected.

Expression Data

Gene:	GFP
Fish:	c368aTg (AB)
Anatomical Terms:	hindbrain pancreas retina spinal cord
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 352(2), Akitake, C.M., Macurak, M., Halpern, M.E., and Goll, M.G., Transgenerational analysis of transcriptional silencing in zebrafish, 191-201, Copyright (2011) with permission from Elsevier. Full text @ Dev. Biol.