FIGURE

Fig. 2

ID

ZDB-FIG-120726-3

Publication

Rhodes et al., 2010 - Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved

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Fig. 2

The effect of rad21 gene dose on the expression of genes regulated downstream of Rad21 in 48 h.p.f. embryos. A-H, quantitative PCR was used to measure the expression of rad21 (A), myca (B), p53 (C), mdm2 (D), ascl1a (E), ascl1b (F), aqp1 (G) and sox11a (H) from cDNA generated from pools of wild type (+/+), heterozygous rad21^nz171 (+/-) and homozygous rad21^nz171 (-/-) embryos. An asterisk indicates where the difference in expression between wild type and heterozygous rad21nz171 is statistically significant (p-value < 0.05). Values are relative to wild type and represent the mean ± s.e.m. of three cDNA samples each run in duplicate.

Expression Data

Genes:	aqp1a.1 ascl1a ascl1b mdm2 myca rad21a sox11a tp53
Fish:	WT rad21a^nz171/nz171 rad21a^nz171/+
Anatomical Term:	whole organism
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 344(2), Rhodes, J.M., Bentley, F.K., Print, C.G., Dorsett, D., Misulovin, Z., Dickinson, E.J., Crosier, K.E., Crosier, P.S., and Horsfield, J.A., Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved, 637-649, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.