FIGURE

Fig. 4

ID

ZDB-FIG-120315-76

Publication

Shen et al., 2012 - The cytokine macrophage migration inhibitory factor (MIF) acts as a neurotrophin in the developing inner ear of the zebrafish, Danio rerio

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Fig. 4

Morpholinos reduced the levels of normal transcripts of mif-like, iclp1, and iclp2. (A) RT-PCR of mif-like transcripts from uninjected, control MO injected, mif morpholinos injected and mif morpholinos plus capped RNAs injected 50-hpf embryos. Predicted size of normal transcript is 512 bp; predicted transcript blocked by mif-like MO = 336 bp. (B) RT-PCR of iclp1 and iclp2 transcripts from control MO-injected, iclp morpholinos injected and iclp morpholinos plus capped RNAs injected 50-hpf embryos. Predicted size of normal iclp1 product = 523 bp, transcript lacking exon 2 = 353 bp. Predicted size of normal iclp2 product = 525 bp, transcript lacking exon 2 = 364 bp.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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Reprinted from Developmental Biology, 363(1), Shen, Y.C., Thompson, D.L., Kuah, M.K., Wong, K.L., Wu, K.L., Linn, S.A., Jewett, E.M., Shu-Chien, A.C., and Barald, K.F., The cytokine macrophage migration inhibitory factor (MIF) acts as a neurotrophin in the developing inner ear of the zebrafish, Danio rerio, 84-94, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.