FIGURE

Fig. 7

ID

ZDB-FIG-101011-20

Publication

Erickson et al., 2010 - Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system

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Fig. 7

Retinal Fgf signalling is upregulated in Meis1-depleted embryos. (A-D) mRNA in situ hybridization (ISH) for the Fgf-responsive genes il17rd/sef (A, B) and dusp6 (C, D) in wild-type (A, C) and meis1 morphant (meis1MO) (B, D) embryos. Dotted lines outline the optic vesicle. The vertical dotted line in (A) indicates the estimated position of the transverse sections in (E-H). Views are dorsal with anterior left. (E-H) Transverse sections through the eyes of 15-hpf wild-type and meis1 morphant embryos stained for il17rd and dusp6. (E′-H′) Detailed views of the corresponding sections in (E-H). The region of interest is indicated by the red dashed-line box. Dotted lines outline the optic vesicles. All transverse sections are oriented with dorsal up. Legend for retinal axial position: D, dorsal; V, ventral; N, nasal; T, temporal; L, lateral; M, medial; A, anterior; P, posterior.

Expression Data

Genes:	dusp6 il17rd
Fish:	AB AB + MO1-meis1b
Knockdown Reagent:	MO1-meis1b
Anatomical Term:	optic vesicle
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-meis1b
Knockdown Reagent:	MO1-meis1b
Observed In:	regulation of fibroblast growth factor receptor signaling pathway
Stage:	10-13 somites

Phenotype Detail

Acknowledgments

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