FIGURE

Fig. 2

ID

ZDB-FIG-091130-1

Publication

Hippe et al., 2009 - The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function

Other Figures

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Fig. 2

Cardiac dysfunction in NDPK B-depleted zebrafish embryos. Cardiac phenotype of wild-type (WT) (A) and NDPK B knockdown (B) embryos at 72 hpf. Fractional shortening (FS) of the atrial and ventricular chamber of WT (C) and NDPK B morphants (D) at 48 and 72 hpf. Data are means ± SEM, n = 11–21. Histology sections of a WT (E) and NDPK B knockdown (F) heart region stained with hematoxylin/eosin. A, atrium, V, ventricle, en, endocardial, my, myocardial layer. (G–J) Whole-mount immunofluorescence following staining with specific antibodies against atrial myosin heavy chain [S46, (G) and (I)] and entire heart tube myosin heavy chain [MF20, (H and J)] showing unaltered expression of structure proteins.

Expression Data

Gene:	myh6
Antibodies:	Ab-MF20 Ab-S46
Fish:	WT WT + MO2-nme2b.1
Knockdown Reagent:	MO2-nme2b.1
Anatomical Terms:	atrium cardiac ventricle
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-nme2b.1
Knockdown Reagent:	MO2-nme2b.1
Observed In:	eye heart heart contraction pericardium
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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