Fig. 5
- ID
- ZDB-FIG-080325-10
- Publication
- Sperber et al., 2008 - Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements
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Effects of dlx1a, and dlx2a loss of function on arch markers. (A, E, and I) Control MO, 0.5 mM; (B, F and J) dlx1aMO, 0.5 mM; (C, G and K) dlx2aMO, 0.25 mM; (D, H, and L) dlx1aMO + dlx2aMO, 0.25 mM each. Expression of (A–D) sox9a, (E–H) neuroD and (I–L) nkx2.3. All panels show dorsal view of flat mounted embryos with anterior to the left. Arrowheads indicate sites of reduced or lost expression. Roman numerals indicate cranial neural crest streams. g, gill arches; ad/av/f, anterodorsal/anteroventral lateral line/facial placode/ganglia; h, hyoid; m, mandibular arch; o, octavel/statoacoustic ganglia precursors; ov, otic vesicle; p, posterior lateral line placode/ganglion. Scale bar: 100 μm. |
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| Stage Range: | Prim-5 to Prim-15 |
Reprinted from Developmental Biology, 314(1), Sperber, S.M., Saxena, V., Hatch, G., and Ekker, M., Zebrafish dlx2a contributes to hindbrain neural crest survival, is necessary for differentiation of sensory ganglia and functions with dlx1a in maturation of the arch cartilage elements, 59-70, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.