Gene
nkx2.3
- ID
- ZDB-GENE-990415-178
- Name
- NK2 homeobox 3
- Symbol
- nkx2.3 Nomenclature History
- Previous Names
-
- nk2.3
- nkx2-3
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in several structures, including cranial ganglion; endoderm; gut; pharyngeal arch; and pharynx. Orthologous to human NKX2-3 (NK2 homeobox 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 48 figures from 39 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Yang et al., 2023
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homedomain-like superfamily | Homeobox, conserved site | Homeobox NK-like transcription regulators | Homeodomain | Homeodomain, metazoa |
|---|---|---|---|---|---|---|
|
UniProtKB:Q98871
|
321 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nkx2.3-201
(1)
|
Ensembl | 1,435 nt | ||
| mRNA |
nkx2.3-202
(1)
|
Ensembl | 814 nt |
Interactions and Pathways
No data available
Plasmids
No data available