FIGURE

Fig. 6

ID

ZDB-FIG-080214-9

Publication

Dal-Pra et al., 2006 - Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity

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Fig. 6

Analysis of double chordin–noggin1 morphants with endomesodermal markers. (A–C) Expression of draculin (drl) specific of presumptive hematopoietic territory at 70% epiboly. (D–F) Expression of the paraxial marker myf5 at the 3-somite stage. (G–I) Expression of the cephalic mesendodermal marker follistatin1 (fst1) at 80% epiboly. (J–L) Expression of the prechordal plate marker hgg1 which labels the presumptive hatching gland at 75% epiboly. (M–O) Expression of the notochordal marker floating-head (flh) at 75% epiboly. (A, D, G, J, M) Wild-type embryos (B, E, H, K, N), 100 μM MO-chd-injected embryos (C, F, I, L, O) 100–800 μM chd-nog1 MOs-injected embryos. (A–C) Vegetal pole views, dorsal to the right. (D–F) Dorsal views anterior to the left. (G–O) Dorsal views, animal pole up.

Expression Data

Genes:	ctslb drl fsta myf5 noto
Fish:	WT WT + MO1-chrd WT + MO1-chrd + MO1-nog1
Knockdown Reagents:	MO1-chrd MO1-nog1
Anatomical Terms:	adaxial cell axial chorda mesoderm paraxial mesoderm prechordal plate presumptive cephalic mesoderm segmental plate ventral mesoderm
Stage Range:	75%-epiboly to 1-4 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 298(2), Dal-Pra, S., Fürthauer, M., Van-Celst, J., Thisse, B., and Thisse, C., Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity, 514-526, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.