FIGURE

Fig. 4

ID

ZDB-FIG-080214-7

Publication

Dal-Pra et al., 2006 - Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity

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Fig. 4

Analysis of double chordin–noggin1 morphants for the expression of tissue-specific molecular markers at 30 hpf. Expression at 30 hpf of three different molecular markers, sox19 labeling the central nervous system, starmaker labeling the otic vesicle and im:7144261 labeling the notochord. (A, E, I, M) Wild-type embryos while the others embryos are injected with MO-chd and MO-nog1 in conditions described in Table 2. (B, F, J, N) Weak aggravation (class I, CI) of the ventralization phenotype, (C, G, K, O) strong ventralization—class II—CII, and (D, H, L, P) extreme ventralization (class 3, CIII). Embryos in lateral view (A–D), (M–P). In dorsal view (E–L), anterior to the left.

Expression Data

Genes:	im:7144261 sox19a stm
Fish:	WT WT + MO1-chrd WT + MO1-nog1 WT + MO1-chrd + MO1-nog1
Knockdown Reagents:	MO1-chrd MO1-nog1
Anatomical Terms:	central nervous system notochord otic vesicle
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-chrd WT + MO1-chrd + MO1-nog1
Knockdown Reagents:	MO1-chrd MO1-nog1
Observed In:	neural plate otic vesicle
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 298(2), Dal-Pra, S., Fürthauer, M., Van-Celst, J., Thisse, B., and Thisse, C., Noggin1 and Follistatin-like2 function redundantly to Chordin to antagonize BMP activity, 514-526, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.