FIGURE SUMMARY
Title

RIP2 Is a Critical Regulator for NLRs Signaling and MHC Antigen Presentation but Not for MAPK and PI3K/Akt Pathways

Authors
Wu, X.M., Chen, W.Q., Hu, Y.W., Cao, L., Nie, P., Chang, M.X.
Source
Full text @ Front Immunol
Fig. 1

RIP2 is critical for embryo hatching and larvae survival. (A) The images of embryos and larvae from WT and RIP2−/− zebrafish at 3 days post-fertilization (dpf). (B) The hatching rate of WT and RIP2−/− zebrafish at 2, 3, 4, and 5 dpf (n = 3, each with 48 embryos). Data represent the mean ± the SEM and were tested for statistical significance using two-tailed Student’s t-test. **p < 0.01, *p < 0.05. (C) The embryo survival curves of WT and RIP2−/− zebrafish (n = 3, each with 48 embryos). (D) The larval survival curves of WT and RIP2−/− zebrafish (n = 3, each with 40 larvae). The survival curves were compared statistically significant difference using the Log-Rank Test. (E) The hatching rate of WT and RIP2−/− zebrafish microinjected with ptGFP1 or ptGFP1-RIP2 at 3, 4, and 5 dpf (n = 2, each with 75 embryos). Data represent the mean ± the SEM, and were tested for statistical significance using two-tailed Student’s t-test. *p < 0.05. (F) The embryo survival curves of WT and RIP2−/− zebrafish microinjected with ptGFP1 or ptGFP1-RIP2 (n = 2, each with 75 embryos). The survival curves were compared statistically significant difference using the Log-Rank Test. The P-values lower than 0.001 were in red.

PHENOTYPE:
Fish:
Observed In:
Stage Range: Prim-5 to Days 7-13
Fig. 4

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. 5

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. 6

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Fig. 7

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Anatomical Term:
Stage Range: Long-pec to Days 7-13
PHENOTYPE:
Fish:
Observed In:
Stage Range: Long-pec to Days 7-13
Fig. 8

ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Immunol
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.
Please check the highlighted fields and try again.
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if additional information is required.
Oops. Something went wrong. Please try again later.