TALEN

TALEN2-nanog

ID

ZDB-TALEN-180423-1

Name

TALEN2-nanog

Previous Names

None

Target

nanog (1)

Target Sequence 1

5' - TTTAACCCATCTTATC - 3'

Target Sequence 2

5' - TGCGGGTACATGAGCC - 3'

Disclaimer

Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.

Note

None

Genome Resources

None

Target Location

Constructs

No data available

Genomic Features

Genomic Feature	Affected Genomic Regions
m1435	nanog

Expression

Gene expression in Wild Types + TALEN2-nanog

No data available

Phenotype

Phenotype resulting from TALEN2-nanog

No data available

Phenotype of all Fish created by or utilizing TALEN2-nanog

Phenotype	Fish	Conditions	Figures
endoderm sox17 expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
yolk microtubule structure, abnormal	nanog^m1435/m1435	standard conditions	Fig. 4 from Veil et al., 2017
yolk syncytial layer morphology, abnormal	nanog^m1435/m1435	standard conditions	Fig. 4 from Veil et al., 2017
whole organism ventral region vent expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 7 from Veil et al., 2017
epiblast bmp2b expression absent, abnormal	nanog^m1435/m1435	standard conditions	Fig. 7 from Veil et al., 2017
whole organism morphology, abnormal	nanog^m1435/m1435	standard conditions	Fig. 1 from Veil et al., 2017
presumptive endoderm sox32 expression absent, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
shield increased size, abnormal	nanog^m1435/m1435	standard conditions	Fig. 1 from Veil et al., 2017
presumptive endoderm gata5 expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
epiboly delayed, abnormal	nanog^m1435/m1435	standard conditions	Fig. 1 from Veil et al., 2017
yolk syncytial layer mxtx2 expression absent, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
blastoderm detached from yolk, abnormal	nanog^m1435/m1435	standard conditions	Fig. 1 from Veil et al., 2017
whole organism her3 expression increased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 7 from Veil et al., 2017
presumptive endoderm mixl1 expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
whole organism ventral region vox expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 7 from Veil et al., 2017
embryo development arrested, abnormal	nanog^m1435/m1435	standard conditions	Fig. 1 from Veil et al., 2017
epiblast vox expression absent, abnormal	nanog^m1435/m1435	standard conditions	Fig. 7 from Veil et al., 2017
presumptive endoderm sox32 expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
endoderm sox17 expression decreased distribution, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
chromatin remodeling disrupted, abnormal	nanog^m1435/m1435	standard conditions	Fig 4 from Pálfy et al., 2020
presumptive mesoderm foxd3 expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
whole organism eomesa expression increased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
presumptive mesoderm tbxta expression decreased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
presumptive endoderm mixl1 expression absent, abnormal	nanog^m1435/m1435	standard conditions	Fig. 3 from Veil et al., 2017
DEL her3 expression increased amount, abnormal	nanog^m1435/m1435	standard conditions	Fig. 7 from Veil et al., 2017
yolk structure, abnormal	nanog^m1435/m1435	standard conditions	Fig. 1 from Veil et al., 2017
yolk syncytial layer actin filament structure, abnormal	nanog^m1435/m1435	standard conditions	Fig. 4 from Veil et al., 2017
yolk syncytial layer cell position, abnormal	nanog^m1435/m1435	standard conditions	Fig. 4 from Veil et al., 2017
endoderm sox17 expression decreased amount, abnormal	nanog^m1435	standard conditions	Fig. 3 from Veil et al., 2017
cell death increased occurrence, abnormal	nanog^m1435	standard conditions	Fig. 2 from Veil et al., 2017
whole organism morphology, abnormal	nanog^m1435	standard conditions	Fig. 1 from Veil et al., 2017
epiboly delayed, abnormal	nanog^m1435	standard conditions	Fig. 1 from Veil et al., 2017
yolk syncytial layer mxtx2 expression absent, abnormal	nanog^m1435	standard conditions	Fig. 3 from Veil et al., 2017
endoderm sox17 expression decreased distribution, abnormal	nanog^m1435	standard conditions	Fig. 3 from Veil et al., 2017
whole organism decreased length, abnormal	nanog^m1435	standard conditions	Fig. 1 from Veil et al., 2017

Citations