Gene

nanog

ID
ZDB-GENE-030131-5486
Name
nanog homeobox
Symbol
nanog Nomenclature History
Previous Names
  • fd20a07
  • nanog-like (1)
  • wu:fd19e04
  • wu:fd20a07 (1)
  • zgc:193933
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Exhibits identical protein binding activity and sequence-specific DNA binding activity. Involved in several processes, including cortical microtubule organization; epiboly; and regulation of gene expression. Predicted to localize to nucleus. Is expressed in several structures, including blastoderm; blastodisc; liver; neuronal stem cell; and reproductive system. Orthologous to several human genes including NANOG (Nanog homeobox).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 12 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
27 figures from 9 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nanog Human Ortholog
No data available
Associated With nanog Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Family IPR050394 Homeobox NK-like transcription regulators
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeobox NK-like transcription regulators Homeodomain
UniProtKB:A5JNG8 384
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nanog-201 (1) Ensembl 2,959 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
AB1-nanog polyclonal Rabbit
  • IHC
  • WB
1
Ab2-nanog polyclonal IgG Rabbit
  • WB
ABclonal
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations