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Fig. 1 Expression pattern of zebrafish Nkd homologs. nkd1 expression is not detectable at 1k-cell stage (A) but ubiquitous during epiboly (B). During somite stages, nkd1 is expressed in somites, rhombomeres and tailbud at 4-somite stage (C) and in cells around the forming KV (D). nkd1 expression at 24 hpf (E). nkd2a is ubiquitously expressed during 1k-cell stage (F), epiboly (G), and in somites, rhombomeres and tailbud at 4-somite stage (H). nkd2a expression in tailbud (I) and at 24 hpf (J). nkd3 ubiquitously expressed during 1k-cell stage (K), epiboly (L), and in somites (M). nkd3 expression in tailbud (N) and at 24 hpf (O). (P–S) nkd1 is expressed ubiquitously throughout gastrulation (P) and in the FCs at 80% epiboly (Q). At 1-somite stage, marked nkd1 expression is observed the tailbud (R), and in cells around the KV (S). Arrows denote DFCs during 80% epiboly, tailbud and 5-somite stage. hpf = hours post fertilization.
Reprinted from Developmental Biology, 348(1), Schneider, I., Schneider, P.N., Derry, S.W., Lin, S., Barton, L.J., Westfall, T., and Slusarski, D.C., Zebrafish Nkd1 promotes Dvl degradation and is required for left-right patterning, 22-33, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.