Gene

alg13

ID

ZDB-GENE-060307-1

Name

ALG13 UDP-N-acetylglucosaminyltransferase subunit

Symbol

alg13 Nomenclature History

Previous Names

otud4 (1)
otul
z-otu (1)

Type

protein_coding_gene

Location

Chr: 21 Mapping Details/Browsers

Description

Involved in dorsal/ventral pattern formation. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 36. Is expressed in blastodisc; ovary; unfertilized egg; and yolk. Orthologous to several human genes including ALG13 (ALG13 UDP-N-acetylglucosaminyltransferase subunit).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Tse et al., 2009
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With alg13 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 36	Alliance	Developmental and epileptic encephalopathy 36	300884

Associated With alg13 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002999	Tudor domain
Domain	IPR003323	OTU domain
Domain	IPR047387	Bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13, OTU domain
Homologous_superfamily	IPR038765	Papain-like cysteine peptidase superfamily

Domain Details Per Protein

Protein	Length	Bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13, OTU domain	OTU domain	Papain-like cysteine peptidase superfamily	Tudor domain
UniProtKB:E9QIU2 InterPro	889
UniProtKB:A0A0R4IPL2 InterPro	854
UniProtKB:Q49HH8 InterPro	859

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	alg13-201 (1) Ensembl	Ensembl	2,837 nt	Select Tool
mRNA	alg13-202 (1) Ensembl	Ensembl	2,820 nt	Select Tool
mRNA	alg13-203 (1) Ensembl	Ensembl	2,711 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-alg13	polyclonal	alg13		Rabbit	IHC		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations