FIGURE

Fig. 3

ID

ZDB-FIG-240425-17

Publication

Nieoczym et al., 2024 - A comprehensive assessment of palmatine as anticonvulsant agent - In vivo and in silico studies

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

PALM’s effect upon the seizure threshold in the MEST (A), 6 Hz-induced psychomotor seizure threshold (B) and timed iv infusion PTZ (C-E) tests in mice. PALM was given ip 30 min prior to the respective seizure test at doses between 10–80 mg/kg. Each experimental group in the MEST and 6 Hz psychomotor seizure tests consisted of 20 animals, while in the iv PTZ test, experimental groups included 8–14 mice. Results from the MEST and 6 Hz seizure tests are presented in the form of median current strengths (CS50 in mA) with their 95% confidence limits as the error bars, while the iv PTZ test results are shown as mean ± SEM. One-way ANOVA and Dunnett’s multiple comparison test was applied for data analysis; * p < 0.05, * * p < 0.01.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomed. Pharmacother.