FIGURE

Figure 9

ID

ZDB-FIG-231127-69

Publication

Cai et al., 2023 - asb5a/asb5b Double Knockout Affects Zebrafish Cardiac Contractile Function

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Figure 9

Atrial morphological changes after asb5a/asb5b inactivation. The 10 s M-mode screenshot clearly displayed the diastolic and systolic shapes of the atrium (A) and ventricle (V). (A) Morphological results. Compared with the other groups, the atrium tissue of the asb5a^−/−:asb5b-ATGmo double-knockout group exhibited significantly longer DD and SD. (B) Statistical results of cardiac SD. Compared with the other groups, the SD of the asb5a^−/−:asb5b-ATGmo double-knockout group was significantly increased. (C) Statistical results of DD. Compared with the other groups, the DD of the asb5a^−/−:asb5b-ATGmo double-knockout group was significantly increased. (D) Statistical results of cardiac fractional shortening. Compared with the other groups, the cardiac fractional shortening in the asb5a^−/−:asb5b-ATGmo double-knockout group was significantly reduced. DD: diastolic diameter; SD: systolic diameter. Plotted values represent means ± SEM (n = 30). ^nsp > 0.05; ** p < 0.01; *** p < 0.001 (unpaired t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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