FIGURE

FIGURE 3

ID

ZDB-FIG-230601-18

Publication

Bai et al., 2023 - Association analysis and functional follow-up identified common variants of JAG1 accounting for risk to biliary atresia

Other Figures

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FIGURE 3

Morphological abnormality of 5dpf zebrafish injected with jag1a and jag1b MOs. (A) Presentative morphology of zebrafish injected with control MO; (B) The typical deformed zebrafish injected with jag1a MOs; (C) The typical deformed zebrafish injected with jag1b MOs; (D) The statistics of malformation rate of jag1a and jag1b morphants were higher than that of control MO group. Except for jag1a-TBMO group, there was significant difference between them and control MO group. Scale bar = 500 μm. All the data are shown as the mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. dpf, day postfertilization; MO, morpholino; SEM, standard error of the mean.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO3-jag1b AB + MO6-jag1a AB + MO7-jag1a AB + MO9-jag1b
Knockdown Reagents:	MO3-jag1b MO6-jag1a MO7-jag1a MO9-jag1b
Observed In:	pericardium post-vent region vertebral column whole organism
Stage:	Day 5

Phenotype Detail

Acknowledgments

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