FIGURE

Figure 3

ID

ZDB-FIG-221214-174

Publication

Poudel et al., 2022 - Regular Supplementation with Antioxidants Rescues Doxorubicin-Induced Bone Deformities and Mineralization Delay in Zebrafish

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Figure 3

Incidence and distribution of skeletal deformities. Incidence of skeletal deformities (a). Partial Least-Squares Discriminant Analysis (PLS-DA score) on the incidence of deformities of zebrafish supplemented with antioxidants, resveratrol (RES), MitoTEMPO (MT), and pro-oxidant, doxorubicin (DOX) (b). Distribution of skeletal deformities (c) and heatmap of distribution of skeletal deformities (d). Statistical significances were calculated using Tukey’s multiple comparisons (one-way ANOVA) [* p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001, **** p ≤ 0.0001] [N = 20 × 4].

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Conditions:	chemical treatment by diet: doxorubicin chemical treatment by diet: antioxidant chemical treatment by diet: doxorubicin chemical treatment by diet: resveratrol chemical treatment by diet: doxorubicin
Observed In:	skeletal tissue
Stage:	Days 30-44

Phenotype Detail

Acknowledgments

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