FIGURE

Figure 1

ID
ZDB-FIG-210915-88
Publication
Schellens et al., 2021 - Zebrafish as a Model to Evaluate a CRISPR/Cas9-Based Exon Excision Approach as a Future Treatment Option for EYS-Associated Retinitis Pigmentosa
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Figure 1

Schematic representation of the domain architecture of human and zebrafish EYS proteins. Both human and zebrafish EYS proteins are comprised of a repetitive protein domain architecture that includes epidermal growth factor (EGF) domains, EGF-like domains and laminin G (LamG) domains. Skipping of eys exon 40-44 results in the exclusion of one LamG and two EGF domains, indicated with a dashed boxed. Numbers indicate amino acids.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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