FIGURE

FIGURE 2

ID

ZDB-FIG-210718-24

Publication

Łysyganicz et al., 2021 - Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia

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FIGURE 2

Level of tubulin acetylation in adult fish eyes. (A) Western blot showing changes in tubulin acetylation in hdac mutants. (B) Quantification of Western blot signals normalized to actin loading controls (Mean with SEM n = 4. One-way ANOVA *p < 0.05, **p < 0.01). ns, no significant.

Expression Data

Antibodies:	Ab1-tuba Ab3-tuba
Fish:	WT hdac6^sh400/sh400 hdac10^sh401/sh401 sirt2^sh626/sh626 hdac6^sh400/sh400; sirt2^sh626/sh626 hdac10^sh401/sh401; hdac6^sh400/sh400 hdac10^sh401/sh401; sirt2^sh626/sh626 hdac10^sh401/sh401; hdac6^sh400/sh400; sirt2^sh626/sh626
Anatomical Term:	eye
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hdac6^sh400/sh400; sirt2^sh626/sh626 hdac10^sh401/sh401; hdac6^sh400/sh400; sirt2^sh626/sh626
Observed In:	eye
Stage:	Adult

Phenotype Detail

Acknowledgments

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