FIGURE

FIGURE 3

ID

ZDB-FIG-210526-17

Publication

Grivas et al., 2021 - Midkine-a Regulates the Formation of a Fibrotic Scar During Zebrafish Heart Regeneration

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FIGURE 3

Loss of mdka leads to heart regeneration arrest. (A–C) AFOG staining of 90 dpci mdka^+/+, mdka^+/cn105, and mdka^cn105 hearts. Collagen is shown in blue, fibrin in red, and healthy myocardium in brown. Scale bar, 100 μm. (D) Quantification of the scar area normalized to the total ventricle area. n_WT = 14, n_KO = 15, n_HET = 14. (E) Percentage of collagen in the scar area. n_WT = n_KO = n_HET = 15. Ordinary one-way anova; *P < 0.05; **P < 0.01; Mean ± SD.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mdka^cn105/cn105
Condition:	cryoablation: cardiac ventricle
Observed In:	cardiac muscle tissue regeneration
Stage:	Adult

Phenotype Detail

Acknowledgments

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