Figure 6

Ultrastructural features of adult WT and mutant skeletal muscle tissue. First, second and third columns present adult WT, desma^kg97/kg97, desmb^kg156/kg156 skeletal muscle tissues’ electron micrographs, respectively. First row indicates the generally aligned sarcomeric structures with the presence of seldom disruptions (a–c, asterisks). Second row shows centrally (d) and peripherally (e,f) located healthy nuclei (N) with peripherally condensed chromatin and well-defined nucleoli. Third and fourth row (g–l) shows pleomorphic mitochondria (M) with well-defined tubular cristae. Fifth and sixth rows present the Z line streaming (arrows in m–o) and enlargement (m–r) of the T-tubule systems related to the triads (double arrows). Uranyl acetate, lead citrate. HM high magnification. Magnifications are as follows: (a–c) 8000 ×, (d) 25,000 ×, (e,f) 20,000 ×, (g–i) 15,000 ×, (j) 40,000 ×, (k) 60,000 ×, (l) 30,000 ×, (m–o) 20,000 ×, (p) 25,000 × and (q,r) 20,000 ×.