FIGURE

Fig. 9

ID

ZDB-FIG-201112-12

Publication

Zhang et al., 2020 - Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish

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Fig. 9

Histological analysis of double and triple knockouts of amh, gdf9 and fshb genes at 3.5 mpf. While double mutation of amh and gdf9 (amh−/−;gdf9−/−;fshb+/−) caused ovarian hypergrowth with PG follicles only, the loss of fshb in the triple knockout (amh−/−;gdf9−/−;fshb−/−) reduced the ovarian size. The ovaries are outlined by dotted lines.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	fshb^umo1/+; gdf9^umo18/+; amh^umo17/+ fshb^umo1/+; gdf9^umo18/umo18; amh^umo17/umo17 fshb^umo1/umo1; gdf9^umo18/+; amh^umo17/umo17 fshb^umo1/umo1; gdf9^umo18/umo18; amh^umo17/umo17
Observed In:	ovary
Stage:	Adult

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and Cellular Endocrinology, 517, Zhang, Z., Zhu, B., Chen, W., Ge, W., Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish, 110963, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.