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Fig. 9 Histological analysis of double and triple knockouts of amh, gdf9 and fshb genes at 3.5 mpf. While double mutation of amh and gdf9 (amh−/−;gdf9−/−;fshb+/−) caused ovarian hypergrowth with PG follicles only, the loss of fshb in the triple knockout (amh−/−;gdf9−/−;fshb−/−) reduced the ovarian size. The ovaries are outlined by dotted lines.
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Reprinted from Molecular and Cellular Endocrinology, 517, Zhang, Z., Zhu, B., Chen, W., Ge, W., Anti-Müllerian hormone (Amh/amh) plays dual roles in maintaining gonadal homeostasis and gametogenesis in zebrafish, 110963, Copyright (2020) with permission from Elsevier. Full text @ Mol. Cell. Endocrinol.