FIGURE

Figure 2

ID

ZDB-FIG-201102-20

Publication

Santhanam et al., 2020 - A Zebrafish Model of Retinitis Pigmentosa Shows Continuous Degeneration and Regeneration of Rod Photoreceptors

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Figure 2

Expression of P23H Flag-tagged rhodopsin at early stages of photoreceptor development in wild type (WT) and P23H transgenic (P23H) zebrafish. Expression of P23H mutant rhodopsin (Flag; red) and rhodopsin (Retp1; green) at 2 dpf (A,B), 3 dpf (C,D), 5 dpf (E,F), 7 dpf (G,H), and 9 dpf (I,J). Expression of Flag-tagged P23H mutant rhodopsin (red) compared to double cones (Zpr1, green) at 2 dpf (K,L), 3 dpf (M,N), 5 dpf (O,P), 7 dpf (Q,R), and 9 dpf (S,T). Yellow arrowheads denote cells expressing P23H mutant rhodopsin. Nuclei labeled with DAPI are blue. ONL: outer nuclear layer; INL: inner nuclear layer. Scale bar in L applies to all panels.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	uth4Tg (AB)
Observed In:	retinal rod cell rod photoreceptor outer segment
Stage Range:	Day 5 to Days 7-13

Phenotype Detail

Acknowledgments

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