FIGURE

Figure 5

ID

ZDB-FIG-201003-45

Publication

Zhang et al., 2020 - An isoflavone derivative potently inhibits the angiogenesis and progression of triple-negative breast cancer by targeting the MTA2/SerRS/VEGFA pathway

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Figure 5

MEQ inhibits the growth of human triple-negative breast cancer (TNBC) xenografts in mice. (A) The growth curves of MDA-MB-231 xenografts in mice treated with MEQ or the dimethyl sulfoxide control. Data are plotted as the mean ± SD. (B, C) At 30 days post-inoculation, the xenografts were dissected and weighted, n = 5. D-H Immunohistochemical staining for SerRS (D), VEGFA (E), CD31 (F), CC3 (G), and Ki67 (H) in the xenografts; n = 5. All scale bars represent 100 μm and all bar graphs are plotted as the mean ± SEM (ns, not significant; *P < 0.05; **P < 0.01; ***P < 0.001 using Student’s t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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