FIGURE

Figure 1

ID
ZDB-FIG-201003-41
Publication
Zhang et al., 2020 - An isoflavone derivative potently inhibits the angiogenesis and progression of triple-negative breast cancer by targeting the MTA2/SerRS/VEGFA pathway
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Figure 1

High throughput screening for compounds that act on the SerRS promoter. (A) Scheme of the dual luciferase reporter-based high throughput screening. (B) Heat map of the luciferase/Renilla ratios for 44 compounds responsive to the SerRS promoter. (C) The molecular structure of MEQ. (D) Relative firefly/Renilla (F/R) ratios for MEQ at indicated dosages and time points. Data are plotted as means ± SEM (n = 3; ns, not significant; **P < 0.01; ***P < 0.001 using Student’s t-test.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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