FIGURE

Fig 3

ID

ZDB-FIG-200718-30

Publication

Deveau et al., 2020 - Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish)

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Fig 3

Antibody stains of 7 dpf larval retinas.

(A) Mutant retina did not have anti-red-opsin or trβ2 reporter fluorescence (N = 4). (B) Heterozygote retina showed the red opsin staining colocalized with tdTomato (N = 4). Images are taken from flattened retinas with the cone outer segments facing upward and in primary focus.

Expression Data

Genes:	rho Tomato
Antibody:	Ab3-rho
Fish:	thrb^nds2/+; q22Tg thrb^nds2/nds2; q22Tg
Anatomical Term:	long double cone cell
Stage:	Days 7-13

Expression Detail

Gene	Antibody	Fish	Conditions	Stage	Qualifier	Anatomy	Assay
rho	ab3-rho	thrb^nds2/+; q22Tg	standard conditions	Days 7-13		long double cone cell	IHC
rho	ab3-rho	thrb^nds2/nds2; q22Tg	standard conditions	Days 7-13	Not Detected	long double cone cell	IHC
Tomato		thrb^nds2/+; q22Tg	standard conditions	Days 7-13		long double cone cell	IFL
Tomato		thrb^nds2/nds2; q22Tg	standard conditions	Days 7-13	Not Detected	long double cone cell	IFL

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Antibody Labeling

No data available

Phenotype Data

Fish:	thrb^nds2/nds2; q22Tg
Observed In:	long double cone cell
Stage:	Days 7-13

Phenotype Detail

Acknowledgments

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