FIGURE

Fig 1

ID

ZDB-FIG-200718-28

Publication

Deveau et al., 2020 - Thyroid hormone receptor beta mutations alter photoreceptor development and function in Danio rerio (zebrafish)

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Fig 1

Two CRISPR mutant lines.

(A) Both mutations are in the first exon of the trβ2 isoform within the N-terminus in the protein binding domain (PBD). Modified from Jones et al. (2003) [14] with permission of Thyroid, Mary Ann Liebert, Inc., publishers, New Rochelle, NY. (B-D) Both mutations targeted the TAT codon resulting in a frameshift indel (6BP+1) and an in-frame codon deletion (3BP). DNA binding domain (DBD), ligand binding domain (LBD).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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