FIGURE

Fig. 9.

ID

ZDB-FIG-200703-34

Publication

Sam et al., 2020 - Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis

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Fig. 9.

Gata6 regulates the number of ventricular cardiomyocytes. Shown are representative images of sibling wild-type (WT) (A) and gata6 null hearts (B) at 2 dpf derived from crossing Tg(myl7:gfp; myl7:dsREDnuc); gata6+/- adults and stained with S46 antibody to distinguish the atrium (blue). Scale bars: 0.1 mm. (C) Quantification of cardiomyocytes in each chamber shows a significant loss of ventricular cardiomyocytes in gata6 homozygous mutants (N=7 per genotype, t-test, P<0.0001, bars shown are s.e.m.). The number of atrial cells in the mutant remains unaffected compared to sibling controls, even though the atrial area is expanded.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gata6^wcm7/wcm7; f2Tg; twu34Tg
Observed In:	atrium cardiac muscle cell cardiac ventricle
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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