FIGURE

Fig. 7.

ID

ZDB-FIG-200703-32

Publication

Sam et al., 2020 - Specificity, redundancy and dosage thresholds among gata4/5/6 genes during zebrafish cardiogenesis

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Fig. 7.

Gata6 regulates ventricular development. ISH was performed at 3 dpf with offspring obtained from crossing either gata5^+/−; gata6^+/− (left panels) or gata4^+/−; gata6^+/− (right panels) double heterozygous adult animals with a probe targeting the ventricular marker vmhc. The gata6 homozygous mutants display smaller ventricles (white arrows) compared to the ventricles in wild-type siblings (the normal size of a wild-type ventricle is shown by the bracketed white line, which helps to indicate relative small size of the chamber in mutant embryos). The gata4 null embryos display progressively smaller ventricles with loss of gata6 alleles (white arrows). Representative scale bars in WT panels: 0.1 mm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gata6^wcm7/wcm7 gata6^wcm7/wcm7; gata4^wcm6/+ gata6^wcm7/wcm7; gata4^wcm6/wcm6
Observed In:	cardiac ventricle
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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