FIGURE

FIGURE 2

ID

ZDB-FIG-190723-165

Publication

Waldron et al., 2019 - Knock-Down of Histidyl-tRNA Synthetase Causes Cell Cycle Arrest and Apoptosis of Neuronal Progenitor Cells in vivo

Other Figures

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FIGURE 2

hars knock-down decreases eye size. (A,B) Quantification of eye diameter relative to body length with (A) increasing doses of hars morpholino and (B) standard morpholino and p53 morpholino controls. (C–F’) Brightfield images of 72 hpf embryos. (C,C’) Uninjected, (D,D’) hars MO, (E,E’) hars MO plus human HARSmRNA, and (F,F’) human HARS mRNA alone. (G,H) Quantification of (G) eye diameter relative to body length and (H) eye area of rescue experiment. Ordinary one-way ANOVA followed by Tukey’s multiple comparisons test was performed (n > = 30 ^∗= 0.05, ^∗∗ = 0.01, ^∗∗∗ = 0.001, ^∗∗∗∗ = < 0.001); the error bars indicate mean and SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	TL + MO1-hars TL + MO1-hars + MO4-tp53
Knockdown Reagents:	MO1-hars MO4-tp53
Observed In:	eye head whole organism
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol