FIGURE

Fig. S4

ID

ZDB-FIG-180828-26

Publication

Gauvrit et al., 2018 - HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development

Other Figures

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Fig. S4

zebrafish hhex mutants exhibit increased hhex expression and the hhex^s722 allele appears to encode a non-functional protein (a-b) Whole-mount in situ hybridization showing hhex expression in 32 hpf hhex^+/+ and hhex^-/- embryos. At 32 hpf, hhex^-/- exhibit increased hhex expression in the vasculature (arrowheads point to ISVs). (c) hhex and hhex^s722 mRNA injection at 50, 100 and 200 pg into one-cell stage wild-type embryos. Injection of wild-type hhex mRNA, but not hhex^s722 mRNA, leads to developmental defects. Scale bars: 100 μm.

Expression Data

Gene:	hhex
Fish:	hhex^s722/s722
Anatomical Term:	endothelial cell
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	hhex^s722/s722
Observed In:	endothelial cell
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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