FIGURE

Fig. S8

ID

ZDB-FIG-180824-34

Publication

Gao et al., 2018 - IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis

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Fig. S8

Direct injection of fertilized zebrafish embryos with Gfap constructs showed mutant-specific tail defects.

Fluorescent imaging showed CNS-specific expression of injected construct Gfap^GFP (A), Gfap^IDH1wt (B) and Gfap^R132C(C) and the corresponding bright-field images (A’-C’). D: the percentage of GFP-positive embryos with tail defects per construct. The ratio of injected embryos with tail defect were calculated based on results of three independent experiments (~100 eggs/construct/experiment). n.s: non-significant. Scale bar: 500μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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