FIGURE

Fig. 1

ID

ZDB-FIG-180808-38

Publication

Ulhaq et al., 2018 - Brain Aromatase Modulates Serotonergic Neuron by Regulating Serotonin Levels in Zebrafish Embryos and Larvae

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Fig. 1

Effect of E₂ on 5-HT-positive area and relative expression of tph isoforms. (A) Representative images of ventral view of head region showing 5-HT-positive cells in pretectal and thalamic complex (ptc) and raphe (r) at 2 dpf. Scale bar: 200 µm. (B,C) Measurements of the area of 5-HT-positive neurons in the experiment of E₂ exposure and co-incubation of E₂ and ICI, respectively. (D,E) Semi-quantitative PCR for expression of tph isoforms in 4 dpf larvae in the experiments of exposure to low and high doses of E₂ and co-incubation with ICI, respectively. Data are presented as a mean ± SEM. Different letters in each graph indicate significant differences (p < 0.05).

Expression Data

Genes:	tph1a tph1b tph2
Antibody:	Ab2-serotonin
Fish:	WT
Conditions:	chemical treatment by environment: 17beta-estradiol chemical treatment by environment: fulvestrant
Anatomical Terms:	diencephalon raphe nucleus whole organism
Stage Range:	Long-pec to Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	chemical treatment by environment: 17beta-estradiol chemical treatment by environment: fulvestrant
Observed In:	diencephalon raphe nucleus whole organism
Stage Range:	Long-pec to Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Endocrinol (Lausanne)