FIGURE

Fig. S2

ID

ZDB-FIG-180620-51

Publication

Cai et al., 2018 - Knockout of zebrafish interleukin 7 receptor (IL7R) by the CRISPR/Cas9 system delays retinal neurodevelopment

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Fig. S2

Retinal development following il7r knockout at 60 hpf. (a-d) HE staining and magnified images of retinas from wild-type (WT, a and b) and il7r^-/- (c and d) embryos. (e-h) Images of Zpr1 or Zpr3 immunofluorescence staining of retinas in WT (e and f) and il7r^-/- (g and h) embryos. (i-j) Statistical analysis of Zpr1-positive signals (i) and Zpr3-positive signals (j) between WT and il7r^-/- retinas. Note that the Zpr1-positive area (i) and Zpr3-positive area (j) are significantly decreased in il7r^-/- retinas. Results are represented as means ± SEM (n=10), ***P<0.001. Scale bar: (a and c), 40 μm; (b and d), 10 μm; (e-h), 50 μm. Abbreviations: GCL: ganglion cell layer; INL: inner nuclear layer; ONL: outer nuclear layer.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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