Fig. 6
- ID
- ZDB-FIG-180103-6
- Publication
- Nagasawa-Masuda et al., 2017 - Yap/Taz transcriptional activity is essential for vascular regression via Ctgf expression and actin polymerization
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Actin polymerization is induced by Yap/Taz transcriptional activity in the CVP. (A, B, and C) Images of a phalloidin stain of indicated embryos at 36 hpf are shown. Embryos of Tg(fli1: gal4dbd-vp16);(UAS: EGFP-hTead2ΔN);(UAS: mCherry) and Tg(fli1: gal4dbd-vp16);(UAS: mCherry) are indicated as hTeadΔN and Gal4-vp16, respectively. White represents the phalloidin stain. Red indicates mCherry signals. Scale bars: 50 μm. Time-dependent change in the phalloidin stain during CVP formation were also analyzed and shown in (C). Solid squares and error bars represent means and SDs. (D) Cell densities of endothelial cells forming the CVP in embryos are shown. Each dot represents one embryo, and solid squares and error bars represent means and SDs. (E) Enlarged images of (A) are shown. Scale bar: 10 μm. |