FIGURE

Fig. 5

ID

ZDB-FIG-180103-5

Publication

Nagasawa-Masuda et al., 2017 - Yap/Taz transcriptional activity is essential for vascular regression via Ctgf expression and actin polymerization

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Fig. 5

Ctgf expression depends on Yap/Taz transcriptional activity in the CVP and is required for dCVP regression.

(A and B) Expression patterns of ctgf mRNA at 28 and 30 hpf are shown. Embryos of Tg(fli1: gal4dbd-vp16);(UAS: EGFP-hTead2ΔN) and Tg(fli1: gal4dbd-vp16) are indicated as hTeadΔN and Gal4-vp16, respectively. A sense probe was used to confirm the specificity of the antisense probe reaction. Enlarged images in (A) are also shown. (C and D) Lateral single-slice images of the CVP region at 36 hpf are shown. Injection (-): embryos not injected; ctgf WT: injected with UAS-zctgfa-EGFP. White color shows mCherry signals. Scale bar: 100 μm. Quantified results are also shown.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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