FIGURE

Fig. 5

ID

ZDB-FIG-171009-13

Publication

Collery et al., 2016 - Loss of Zebrafish Mfrp Causes Nanophthalmia, Hyperopia, and Accumulation of Subretinal Macrophages

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Zebrafish mfrp mutants show subretinal microglia/macrophages. (A, B, C) Cells in the subretinal space of mfrp mutant zebrafish stain positively with a microglia/macrophage marker (antibody 4C4; red arrows), whereas control heterozygous and wild-type sibling zebrafish lack such staining in the subretinal space. Resident microglia in the inner retina also stain with this marker (red arrowheads). (D, E) A pigmented subretinal cell, likely a macrophage, is visible among the photoreceptor outer segments in an mfrp mutant plastic section (red arrow). These pigmented cells are not seen in controls. Scale bars: (A–F) 100 μm; (G–H) 20 μm.

Expression Data

Antibody:	Ab-4C4
Fish:	WT mfrp^mw78/mw78 mfrp^mw78/+
Anatomical Term:	eye microglial cell
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Invest. Ophthalmol. Vis. Sci.