FIGURE

Fig. 3

ID

ZDB-FIG-170807-23

Publication

Passoni et al., 2017 - Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and chikungunya viruses favour different entry routes

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

CHIKV, but not SINV, infects the brain microvascular endothelium. Dorsal views of fli:G/U:RFP larvae, with infected cells in green and endothelial cells shown in magenta; confocal imaging, maximal projections. For all panels, the top image (with ′) shows superposition of transmitted light with green and magenta fluorescence, and the bottom image (with ″) shows only the magenta fluorescence to provide better visualization of the vasculature. Scale bars: 50 μm. (A,B) Live imaging of the same SINV-infected larva at 1 dpi (A) and 2 dpi (B). See also Fig. S1A, Movies 1 and 2, for a view through the z-stack. (C) Live imaging of control uninfected (No V) larva. (D,E) Fixed CHIKV-infected larvae at 1 dpi (D) and 2 dpi (E). See also Fig. S1B and Movie 4, for a view through the z-stack. (F) Fixed IHNV-infected larva at 2 dpi. See also Movie 5, for a view through the z-stack. In this and all following dorsal view figures, anterior is to the left.

Expression Data

Gene:	RFP
Fish:	nkuasrfp1aTg; ubs4Tg
Conditions:	viral treatment by injection: Chikungunya virus viral treatment by injection: Infectious hematopoietic necrosis virus viral treatment by injection: Sindbis virus
Anatomical Term:	endothelial cell
Stage Range:	Day 4 to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.