FIGURE

Fig. 4

ID

ZDB-FIG-161116-12

Publication

Almeida et al., 2016 - Oligodendrocyte Development in the Absence of Their Target Axons In Vivo

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Fewer oligodendrocytes mature in the posterior but not anterior spinal cord of kbp mutants.

A, Spinal cord of 96hpf Tg(mbp:EGFP) larvae with mature oligodendrocyte somas labelled. The myelin sheath of the very large diameter Mauthner axon (M), a reticulospinal axon, is visible in the ventral spinal cord except in the posterior region of mutants. Scale bar: 25 μm. B, The number of total, ventral and dorsal oligodendrocytes (OLs) is reduced in a 425μm long region of the posterior but not anterior spinal cord in mutants, compared to WTs. Data from N = 11 WT and N = 10 mutants (anterior) and N = 20 WT and N = 14 mutants (posterior). * indicates P<0.05; *** indicates P<0.001; see text for details. Error bars indicate ± SD.

Expression Data

Gene:	EGFP
Fish:	ue1Tg kifbp^st23/st23; ue1Tg
Anatomical Term:	spinal cord oligodendrocyte
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	kifbp^st23/st23; ue1Tg
Observed In:	Mauthner neuron myelin sheath Mauthner neuron posterior region oligodendrocyte spinal cord posterior region spinal cord postero-dorsal region spinal cord postero-ventral region
Stage:	Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One