FIGURE

Fig. S4

ID

ZDB-FIG-160218-22

Publication

Jahangiri et al., 2016 - The AP-1 transcription factor component Fosl2 potentiates the rate of myocardial differentiation from the zebrafish second heart field

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Fig. S4

Developmental expression profiles of AP-1 components fosl2, c-jun, and c-fos.

(A, B) In situ hybridization analysis of fosl2 transcripts at the 12 somites stage (ss) (A) and 42 hours post fertilization (hpf) (B). The embryo shown in (B) is co-stained for the myocardial transcript cmlc2. The arrowhead in (B) highlights fosl2 expression in pharyngeal mesoderm on the extra-cardiac side of the arterial pole where SHF progenitors reside. (C-F) Double in situ hybridization analysis of c-jun and cmlc2 transcripts at 26 hpf (C-E) and 36 hpf (F). Double stained embryos shown in (D) were washed with methanol to remove the cmlc2 signal and photographed again (E). C-jun+ cells were observed on either side of the arterial pole. Arrowhead in (F) highlights c-jun expression in pharyngeal mesoderm on the extra cardiac side of the arterial pole where SHF progenitors reside. In all cases, greater than 20 embryos were analyzed.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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