FIGURE
Fig. 7
- ID
- ZDB-FIG-160208-36
- Publication
- Shen et al., 2015 - Down-regulation of msrb3 and destruction of normal auditory system development through hair cell apoptosis in zebrafish
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Fig. 7
Msrb3 morphants are profoundly deaf. (A,C) Examples of C-shaped startle responses of different larval types after sound stimuli (500 Hz; 10 ms). The escape response of control larvae was initiated 5-13 ms after the sound stimulation. Abnormal swimming behavior of msrb3 morphants indicated a defective balance system. Some morphants had no response to voice stimulation. After co-injection with human MSRB3A mRNA (hM3A), In2MO and Ex2MO zebrafish regained some hearing. (B,D) Average C-startle response probability. For each group, 30 larvae were tested. *** P<0.0001. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
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Full text @ Int. J. Dev. Biol.