FIGURE

Fig. S3

ID

ZDB-FIG-150602-10

Publication

Hirose et al., 2014 - Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins

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Fig. S3

p-S6K signals were markedly reduced by 3 or 6 h treatment with inhibitors (rapamycin, Torin1, and AZD8055). (A) Scheme of rapamycin, Torin1, or AZD8055 treatment from 24 h to 27 or 30 hpa. (B-I) Longitudinal sections of wild-type fin regenerates that were immunohistochemically stained with an antibody against p-S6K (green) at 27 hpa (DMSO, n = 3; Rapa, n = 3; Torin1, n = 3; AZD8055, n = 3) or 30 hpa (DMSO, n = 3; Rapa, n = 3; Torin1, n = 3; AZD8055, n = 3). DAPI fluorescent signal (blue) indicates the presence of nuclei. The p-S6K signals were markedly reduced by 3 or 6 h treatment with inhibitors (rapamycin, Torin1, and AZD8055). Dashed white lines indicate the amputation plane. Scale bars: 100 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.