FIGURE

Fig. 8

ID

ZDB-FIG-150319-25

Publication

Cheng et al., 2015 - The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis

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Fig. 8

Resemblance between the phenotypes of her2^ΔbHLH- or her2^ΔWRPW-injected embryos and those of her2 morphants. (A) Schematic illustration of her2^ΔbHLH and her2^ΔWRPW deletion constructs. (B) In situ hybridization showing injection of either her2^ΔbHLH or her2^ΔWRPW was sufficient to downregulate markers for neural progenitors and neuronal and glial derivatives, as observed in Her2 morphants. The stages of the embryos are shown in the bottom- left corner. These results were confirmed by qPCR (C). ^*, p<0.05; ^**, p<0.01.

Expression Data

Genes:	dla gfap neurog1 slc1a3a sox2
Fish:	TU
Anatomical Terms:	glioblast neuroblast radial glial cell
Stage Range:	75%-epiboly to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 397(1), Cheng, Y.C., Chiang, M.C., Shih, H.Y., Ma, T.L., Yeh, T.H., Huang, Y.C., Lin, C.Y., Lin, S.J., The transcription factor hairy/E(spl)-related 2 induces proliferation of neural progenitors and regulates neurogenesis and gliogenesis, 116-28, Copyright (2015) with permission from Elsevier. Full text @ Dev. Biol.