FIGURE

Fig. S6

ID

ZDB-FIG-150313-13

Publication

Casari et al., 2014 - A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development

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Fig. S6

Tg(12xSBE:EGFP)ia16 line is responsive to the overexpression of smad3b, and smad3a together with smad3b: effects of mRNA injection on embryos with a malformed phenotype. Brightfield and fluorescent images of head and tail of 24 hpf embryos injected with smad2, 3a, 3b and 4 mRNAs. The last column shows a zoomed view of the tails. White arrow heads in fluorescent head pictures point out the cardiac mesoderm. Injection of smad3b and smad3a+smad3b mRNAs causes an increase of GFP expression in this area. In the same injected embryos overexpression of GFP is also visible in tail mesoderm (white arrow heads).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 396(1), Casari, A., Schiavone, M., Facchinello, N., Vettori, A., Meyer, D., Tiso, N., Moro, E., Argenton, F., A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development, 81-93, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.