Fig. 7
- ID
- ZDB-FIG-140425-14
- Publication
- Han et al., 2014 - The Nogo-C2/Nogo receptor complex regulates the morphogenesis of zebrafish lateral line primordium through modulating the expression of dkk1b, a Wnt signal inhibitor
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Knockdown of p75, TROY, or Nogo-C2/NgRH1a resulted in disordered morphogenesis of the PLL primordium during caudal migration. (A) Transgenic CldnB::lynEGFP zebrafish were injected with control MO (panel a), or MOs against zebrafish p75 (panel b), TROY (panel c), or Nogo-C2/NgRH1a (panel d), and time-lapse recording was then performed from 28 hpf. The morphology of PLL primordium in the morphants was unstable during migration, as shown at 30-min intervals (panels b–d). (B) Rosette formation in control (panel a), p75 (panel b), TROY (panel c), and Nogo-C2/NgRH1a (panel d) morphants. Rosettes are indicated by red arrows. Scale bar, 20 μm. |
| Gene: | |
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| Fish: | |
| Knockdown Reagents: | |
| Anatomical Term: | |
| Stage: | Prim-5 |
| Fish: | |
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| Knockdown Reagents: | |
| Observed In: | |
| Stage: | Prim-5 |