FIGURE

Fig. 3

ID

ZDB-FIG-140425-12

Publication

Han et al., 2014 - The Nogo-C2/Nogo receptor complex regulates the morphogenesis of zebrafish lateral line primordium through modulating the expression of dkk1b, a Wnt signal inhibitor

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Defects in neuromast formation were observed in both Rtn4-m/Nogo-C2 and NgRH1a morphants.

Zebrafish embryos were injected with morpholinos against the indicated zebrafish Nogo-related ligand or Nogo receptor at the 2~4-cell stage. Neuromast formation in these morphants was observed by staining with 4-Di-2-ASP at 72 h post-fertilization (hpf). A control embryo is shown in panel (A). Images were taken from the lateral view, and the yellow dots indicate neuromasts of the zebrafish lateral line. Scale bar, 100 μm. A summary of PLL neuromast numbers in MO-injected embryo is shown in panel (I). Sample size (N) and MO dosage used are indicated.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-rtn4rl2a WT + MO7-rtn4a
Knockdown Reagents:	MO1-rtn4rl2a MO7-rtn4a
Observed In:	posterior lateral line neuromast
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One