FIGURE

Fig. 4

ID

ZDB-FIG-131015-62

Publication

Rothschild et al., 2013 - CaMK-II activation is essential for zebrafish inner ear development and acts through Delta-Notch signaling

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Fig. 4

Motile cilia and kinocilia form in camk2g1 morphants. Control (A, D) and camk2g1 morphants (B, D) were labeled with anti-acetylated tubulin (green) at 21ss and at 24 hpf. Kinocilia formed in the proper locations (arrows) emerging from hair cells at the anterior and posterior poles of the otic vesicle. Anterior is to the left. Scale bars=5 μm. A histogram of the number of kinocilia per otic vesicle (OV) pole at 24 hpf (E) revealed a shift in morphant embryos (n=43) to higher values when compared to control embryos (n=62).

Expression Data

Antibody:	Ab1-tuba
Fish:	WT WT + MO1-camk2g1
Knockdown Reagent:	MO1-camk2g1
Anatomical Term:	auditory receptor cell kinocilium
Stage Range:	20-25 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-camk2g1
Knockdown Reagent:	MO1-camk2g1
Observed In:	otic vesicle kinocilium
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 381(1), Rothschild, S.C., Lahvic, J., Francescatto, L., McLeod, J.J., Burgess, S.M., and Tombes, R.M., CaMK-II activation is essential for zebrafish inner ear development and acts through Delta-Notch signaling, 179-88, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.